Organoids are carrying the promise of modeling complex disease phenotypes and serving as a powerful basis for unbiased drug screens, potentially offering a more efficient drug-discovery route. However, unsolved technical bottlenecks of reproducibility and scalability have prevented the use of current organoids for high-throughput screening. Here, we present a method that overcomes these limitations by using deep-learning-driven analysis for phenotypic drug screens based on highly standardized micropattern-based neural organoids.

Utilizing the powerful combination of molecular-beam epitaxy (MBE) and angle-resolved photoemission spectroscopy (ARPES), we produce and study the effect of different terminating layers on the electronic structure of the metallic delafossite PdCoO2. Attempts to introduce unpaired electrons and synthesize new antiferromagnetic metals akin to the isostructural compound PdCrO2 have been made by replacing cobalt with iron in PdCoO2 films grown by MBE. Using ARPES, we observe similar bulk bands in these PdCoO2 films with Pd-, CoO2-, and FeO2-termination.

Piezomagnetism couples strain linearly to magnetic order, implying that it can produce and control magnetization. However, unlike magnetostriction, which couples magnetization quadratically to strain, it enables bidirectional control of a net magnetic moment. If this effect becomes large at room temperature, it may be technologically relevant, similar to its electric analogue, piezoelectricity. However, current studies of the piezomagnetic effect have been primarily restricted to antiferromagnetic insulators at cryogenic temperatures.

Background: Porous polymer scaffolds are commonly used for regenerative medicine and tissue-engineered therapies in the repair and regeneration of structural tissues which require sufficient mechanical integrity to resist loading prior to tissue ingrowth. Objective: Investigate the connection between scaffold architecture and mechanical response of collagen scaffolds used in human tissue-engineered cartilage. Methods: We performed multi-scale mechanical analysis on two types of porous collagen scaffolds with honeycomb and sponge architectures.

The semiclassical description of two-dimensional (2d) metals based on the quasiparticle picture suggests that there is a universal threshold of the resistivity: the resistivity of a 2d metal is bounded by the so called Mott-Ioffe-Regal (MIR) limit, which is at the order of h/e2. If a system remains metallic while its resistivity is beyond the MIR limit, it is referred to as a "bad metal", which challenges our theoretical understanding as the very notion of quasiparticles is invalidated.

Critical thinking is the process by which people make decisions about what to trust and what to do. Many undergraduate courses, such as those in biology and physics, include critical thinking as an important learning goal. Assessing critical thinking, however, is non-trivial, with mixed recommendations for how to assess critical thinking as part of instruction. Here we evaluate the efficacy of assessment questions to probe students' critical thinking skills in the context of biology and physics.

What limits the value of the superconducting transition temperature (Tc) is a question of great fundamental and practical importance. Various heuristic upper bounds on Tc have been proposed, expressed as fractions of the Fermi temperature, TF, the zero-temperature superfluid stiffness, ρs(0), or a characteristic Debye frequency, ω0. We show that while these bounds are physically motivated and are certainly useful in many relevant situations, none of them serve as a fundamental bound on Tc.

We report measurements of antiferromagnetic resonances in the van der Waals easy-axis antiferromagnet CrSBr. The interlayer exchange field and magnetocrystalline anisotropy fields are comparable to laboratory magnetic fields, allowing a rich variety of gigahertz-frequency dynamical modes to be accessed. By mapping the resonance frequencies as a function of the magnitude and angle of applied magnetic field, we identify the different regimes of antiferromagnetic dynamics.

Low-energy miniemulsions enable the production of uniform nanodroplets for a wide range of applications without the need for using specialized equipment. However, low-energy miniemulsions are typically formed in the presence of a surface-active agent with a specific structure and property.

Quantum information processing relies on the precise control of non-classical states in the presence of many uncontrolled environmental degrees of freedom. The interactions between the relevant degrees of freedom and the environment are often viewed as detrimental, as they dissipate energy and decohere quantum states. Nonetheless, when controlled, dissipation is an essential tool for manipulating quantum information: dissipation engineering enables quantum measurement, quantum-state preparation and quantum-state stabilization.