A quantum anomalous Hall (QAH) insulator is characterized by quantized Hall and vanishing longitudinal resistances at zero magnetic field that are protected against local perturbations and independent of sample details. This insensitivity makes the microscopic details of the local current distribution inaccessible to global transport measurements. Accordingly, the current distributions that give rise to transport quantization are unknown. Here we use magnetic imaging to directly visualize the transport current in the QAH regime.

Interacting electrons in flat bands give rise to a variety of quantum phases. One fundamental aspect of such states is the ordering of the various flavours - such as spin or valley - that the electrons can undergo and the excitation spectrum of the broken symmetry states that they form. These properties cannot be probed directly with electrical transport measurements.

Uncertainty is an important and fundamental concept in physics education. Students are often first exposed to uncertainty in introductory labs, expand their knowledge across lab courses, and then are introduced to quantum mechanical uncertainty in upper-division courses. This study is part of a larger project evaluating student thinking about uncertainty across these contexts.

Cell fate decisions emerge as a consequence of a complex set of gene regulatory networks. Models of these networks are known to have more parameters than data can determine. Recent work, inspired by Waddington's metaphor of a landscape, has instead tried to understand the geometry of gene regulatory networks. Here, we describe recent results on the appropriate mathematical framework for constructing these landscapes. This allows the construction of minimally parameterized models consistent with cell behavior.

Etoposide is a broadly employed chemotherapeutic and eukaryotic topoisomerase II poison that stabilizes cleaved DNA intermediates to promote DNA breakage and cytotoxicity. How etoposide perturbs topoisomerase dynamics is not known. Here we investigated the action of etoposide on yeast topoisomerase II, human topoisomerase IIα and human topoisomerase IIβ using several sensitive single-molecule detection methods. Unexpectedly, we found that etoposide induces topoisomerase to trap DNA loops, compacting DNA and restructuring DNA topology.

Stabilizer codes allow for non-local encoding and processing of quantum information. Deformations of stabilizer surface codes introduce new and non-trivial geometry, in particular leading to emergence of long sought after objects known as projective Ising non-Abelian anyons. Braiding of such anyons is a key ingredient of topological quantum computation. We suggest a simple and systematic approach to construct effective unitary protocols for braiding, manipulation and readout of non-Abelian anyons and preparation of their entangled states.

Recent studies have given incentives to physics departments around the world to revise the learning goals of their lab courses to emphasize experimentation skills over reinforcing lecture content. Evaluation instruments have been developed to measure the achievement of learning goals, and one such instrument is the Physics Lab Inventory of Critical thinking (PLIC). The PLIC measures respondents’ ability to evaluate models, evaluate methods, and to suggest the next steps for an investigation.

Tissue-engineered cartilage constructs have shown promise to treat focal cartilage defects in multiple clinical studies. Notably, products in clinical use or in late-stage clinical trials often utilize porous collagen scaffolds to provide mechanical support and attachment sites for chondrocytes. Under loading, both the local mechanical responses of collagen scaffolds and the corresponding cellular outcomes are poorly understood, despite their wide use.