Skip to main content

The linac coherent light source single particle imaging road map

Cornell Affiliated Author(s)


A. Aquila
A. Barty
C. Bostedt
S. Boutet
G. Carini
D. DePonte
P. Drell
S. Doniach
K.H. Downing
T. Earnest
H. Elmlund
V. Elser
M. Gühr
J. Hajdu
J. Hastings
S.P. Hau-Riege
Z. Huang
E.E. Lattman
F.R.N.C. Maia
S. Marchesini
A. Ourmazd
C. Pellegrini
R. Santra
I. Schlichting
C. Schroer
J.C.H. Spence
I.A. Vartanyants
S. Wakatsuki
W.I. Weis
G.J. Williams


Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources. © 2015 Author(s).

Date Published


Structural Dynamics








Group (Lab)

Veit Elser Group

Download citation