Biological physics uses the tools and techniques of physics to understand the workings of the molecular machinery of life, and it also applies knowledge of the way things work at the molecular level to other problems in the physical sciences. Cornell supports a growing range of activities in biological physics, including investigations into fluctuations in biological systems, imaging of molecular motion, the operation of molecular motors, properties of biological macromolecules, interactions in living cells, biomembrane structure and function, mechanical properties of chromosomes and biological macromolecules, molecular diffusion and receptor-ligand interactions on membranes, and ion channel dynamics.

Physicists bring a quantitative approach to the study of biology, and an orientation toward seeking understanding at a fundamental level that is readily generalized to other systems. A defining characteristic of biological physics is the development of new instruments and techniques to better probe and manipulate biological materials.

Examples of this research include:

• the combination of optical traps with high-precision detection to manipulate DNA, which aids in understanding how DNA gets packed and in observing the transcription of DNA to RNA.
• the use of nanofabricated cells and synchrotron x-ray techniques to monitor protein folding.
• the application of techniques of solid state crystal growth to better understand the process of protein crystallization.

Also see the Cornell Biophysics Colloquia.